|Maturation stages of the 5 types of White Cells|
When a lab tech reviews a slide of a patient they are looking at the cells in the peripheral blood that has been drawn from your vein. Under the microscope in a normal patient all the cells will be small ,but an abnormal patient the white cells when viewed under the microscope will be large and small because immature cells will also be seen.
|Myelogenous Leukemia in Peripheral Blood Smear|
In Special Hematology they will perform a flow cytometry. This procedure is where cells are suspended in stream of fluid and the cells and and chromosomes by passing them by an electronic apparatus to identify the cells.
In the genetic testing they will need to find out if there is a chromosomal translocation in the Philadelphia chromosome which is a characteristic of CML.
Symptoms of CML are the following:
1. weight loss
3. hip and joint pain
4. susceptible to infections
5. low grade fever
6. abnormal platelet count
If you are experiencing any of these symptoms you need to see a healthcare professional.
CML is treated with inhibitors of tyrosine kinase such as Gleevec.
The prognosis for CML is good if the patient is pro-active in taking medications and regular visits to the their oncologist.